
Paste any ingredient list to check it for pore clogging, fungal acne, rosacea, eczema and sensitive skin triggers, with a study linked to every flag.

Red and amber are what the yeast feeds on. Green is the antifungals that help.
- Key:
- ✕Flagged or a trigger
- !Worth watching
- ✓May help
- ○Lab or animal only, or tested fine
- Key:
- ✓Strong evidence
- ✓Some evidence
- ?Early or small studies
- !Watch in the sun
- ✕Avoid
- ○Lab or animal only
- Key:
- ✓Strong evidence
- ✓Some evidence
- ?Early or small studies
- ○Lab or animal only
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How it works, FAQs and sources
Paste an ingredient list into the box below and pick what you’re checking for. Malassezia (the yeast linked to fungal acne and seb derm), rosacea, pore-clogging (comedogenic) ingredients, or anti-ageing ingredients with real research behind them. The checker reads every single ingredient and shows you both sides. Red and amber are the ones to watch out for, green is the good stuff with research behind it, and every result comes with a quick line on why and a source. The anti-ageing tab is the only one that just grades the good stuff. It works on shampoos, conditioners and scalp serums too, not just face products.
It uses the same rules I screen products with for my seb derm directories. That makes it a little strict on purpose (I’d rather flag something and let you decide). A flag is only a heads up though. Loads of people use flagged products and get on fine with them, so patch test and trust your own skin.
How the checker decides what to flag
Fungal acne and seb derm (malassezia)
For malassezia, red means ingredients the yeast is known to feed on. Thats most plant oils and butters, plus fatty acids and the esters made from them in the C11 to C24 range (laurates, stearates, palmitates, oleates) and polysorbates. Amber means the evidence is thinner or the checkers don’t agree. Fatty alcohols, ferments and lecithin all land there. Nobody has actually tested whether ferments feed the yeast, and some dermatologists say plenty of fungal acne-prone skin gets on fine with them, which is why they stay amber rather than red. The one exception is Vitreoscilla ferment (in La Roche-Posay and Vichy products), which has a small seb derm trial of its own, so it gets a mild green.
Cetearyl alcohol is the tricky one. A 2019 lab study by Dobler and colleagues saw some malassezia growth on it, especially from one species (M. furfur). SkinSort and Folliculitis Scout both flag it, but that one lab study is most of the evidence, so I mark it amber and you make the call. The same study found lanolin barely fed the yeast, and coco-caprylate/caprate fed two of the four species tested, so both get an amber too. MCT oil (caprylic/capric triglyceride) shows up in grey as lab only, because lab studies found it doesn’t feed the yeast and may even slow it down. Petrolatum and mineral oil stay clear. One yeast species grew slowly on them in the lab, but the main dandruff species didn’t, and most fungal acne checkers call them safe. Castor oil is the one plant oil that gets an amber instead of a red, because only one yeast species (M. furfur) could feed on it in two lab studies. C12-15 alkyl benzoate, the sunscreen emollient, gets an amber too, because the checkers disagree on it (its long chains are on the alcohol side, not the acid side). Natural waxes (beeswax, candelilla, carnauba, rice bran and sunflower wax) get an amber as well, since SkinSort says the yeast can break them down but nobody has tested it. Petroleum waxes like microcrystalline wax and paraffin stay clear, the same as petrolatum. Coco-glycerides and olive esters go red, because they’re made from the same fatty acids as coconut and olive oil. Beef tallow (the tallow balm trend) goes red too, since it’s the same kind of fat, and tallow soap (sodium tallowate) gets the soap amber. Neem leaf shows in grey as lab only, while neem oil gets the plant oil red.
Essential oils don’t get flagged in malassezia mode. They’re mostly terpenes rather than the fats in carrier oils, so they aren’t counted as yeast food. Flip over to rosacea mode and they light up.
Seb derm and fungal acne share the first button because they’re driven by the same yeast, so the same ingredients get flagged for both. For a seb derm scalp, the leave-in products are the ones worth checking hardest, because a shampoo rinses off in a minute and a serum sits there all day.
This mode also picks out the ingredients that fight the yeast rather than feed it: ketoconazole, ciclopirox, piroctone olamine, zinc pyrithione and selenium sulfide. They show up in green as “may help seb derm”, each with its source. A green one in a shampoo is good news, but it needs time on the scalp to do anything, so check the label for how long to leave it on before you rinse.
The same American Family Physician review adds a few more greens: coal tar, tea tree oil shampoo, azole antifungals like sertaconazole and climbazole, and the prescription creams pimecrolimus and tacrolimus. Salicylic acid and sulfur go green too, because they help lift the scale even though they don’t kill the yeast. On the other side, squalene (with an e) and lanolin now get an amber, since SkinSort flags both. Squalane with an a is still fine. Lithium gluconate gets a green too (a 288-person trial found it beat ketoconazole cream on the face), and so do Quassia amara and aloe vera, which each have one small seb derm trial. Honey gets a mild green too, from one small study where people left crude honey on for hours. So does propylene glycol (a small scalp trial used 15%, which is far more than most products have), and hydrocortisone gets one for short flare-ups. The prescription creams roflumilast and ivermectin get greens too, and rosemary extract gets a mild one for scalp itch (the extract, not rosemary oil). Myrtle extract and a chlorhexidine scalp rinse get mild greens from dandruff trials too, and sertaconazole cream gets a full green from a review of 8 trials. Econazole and miconazole keep their green for seb derm, but in one small study they did badly for fungal acne on the body, so their notes say so. Green tea gets a mild green here too, from a small review of green tea shampoo for scalp seb derm. Metronidazole (the rosacea cream) gets a mild green with a caveat, because its seb derm trials disagree. Terbinafine cream (the athlete’s foot one) gets a full green, after beating a placebo in a 90-person trial. Hypochlorous acid sprays get a mild green from small seb derm studies, and so does glycyrrhetinic acid (from licorice), after a small shampoo study cut the main dandruff yeasts. Lemongrass oil gets a mild green from a small placebo-controlled dandruff trial (it’s still red in rosacea mode, like every essential oil). They don’t get a green in rosacea mode, because I couldn’t find a rosacea trial.
Rosacea triggers
For rosacea, the list comes from National Rosacea Society patient surveys and the American Academy of Dermatology’s rosacea advice. Alcohol, fragrance, witch hazel and menthol came out on top, with peppermint and eucalyptus close behind, so those are red. Amber covers the stuff that bothers some people and not others, like exfoliating acids, sulfates, dyes and fragrance allergens such as linalool and limonene. In 2023 the EU added dozens more fragrance allergens to the list brands must name on labels, so the checker flags those too, including linalyl acetate, vanillin, benzaldehyde, pinene, terpineol, methyl salicylate, santalol, Iso E Super and Galaxolide.
Everyone’s rosacea is different, so your own triggers might not be on here at all. You might sail through half the red ones too. One tip from the American Academy of Dermatology: pick products labelled fragrance-free rather than unscented, because unscented doesn’t always mean no fragrance was added.
Rosacea mode has green flags as well, for the ingredients with evidence of actually helping. Azelaic acid is the main one you’ll find in shop-bought skincare, and niacinamide gets a green too (one small moisturizer study, so it’s a mild green). Zinc oxide and titanium dioxide go green because the American Academy of Dermatology says mineral sunscreen is the least likely kind to irritate rosacea skin. And if you paste in a prescription cream, it picks out metronidazole, ivermectin, minocycline, brimonidine and oxymetazoline too.
The soothing K-beauty favourites get milder greens. Centella (madecassoside, cica) has one small rosacea trial, panthenol has barrier research on irritated skin, Bifida ferment lysate has a small trial on sensitive skin, and green tea has a review that’s hopeful but thin on human studies. A few popular calming ingredients (Scutellaria baicalensis, mugwort and heartleaf) only have lab or animal research so far. They show up in grey as “lab or animal only”, with the study linked, but they don’t get a green. That doesn’t mean they’re bad for you (the checker just won’t give credit without human evidence).
A few more greens come from trials and from the American Family Physician rosacea review: sulfur, Chrysanthellum indicum (a 246-person trial), licochalcone A and glycyrrhetinic acid from licorice, milk thistle (silymarin), tranexamic acid, Quassia amara, kinetin, honey (a 138-person trial), oat and aloe, timolol eye drops, permethrin cream, parthenolide-free feverfew, potassium azeloyl diglycinate (a gentler azelaic acid), hyaluronic acid (one small open study), ceramides and gentle PHAs like gluconolactone. Plain licorice root extract (Glycyrrhiza glabra) and dipotassium glycyrrhizate don’t get a green, because I couldn’t find a rosacea study of either on the skin. That same review adds to the avoid list too, so acetone, scrubbing grains, astringents like alum, niacin-type ingredients and topical steroids now get flagged. Patch test studies add a few more ambers: gallates, BHT and TBHQ, cocamidopropyl betaine, formaldehyde-releasing preservatives, propolis and balsam of Peru. People with rosacea turn out to be allergic to cosmetic ingredients far more often than people without it, so these are about allergy rather than rosacea itself. The American Contact Dermatitis Society’s Allergens of the Year add a few more ambers of the same kind: lanolin, propylene glycol, the glucoside cleansers (decyl, lauryl and coco glucoside), benzophenone sunscreen filters and sulfites. Oakmoss and treemoss get one too, as classic perfume allergens the EU has restricted. So do the preservatives IPBC and benzalkonium chloride, and the daisy family plants often sold as calming (chamomile, arnica, calendula, yarrow, tansy, dandelion, echinacea and chrysanthemum), which share an allergen group. More patch test ambers: colophony (rosin, in some mascaras and lipsticks), gallates, cocamide DEA, the amidoamine conditioners, shellac, sorbitan sesquioleate and ethylhexylglycerin. Octocrylene and avobenzone get one too, as the chemical sunscreen filters most often behind sun-triggered allergy. Fragrant plant extracts the EU now lists as allergens (lavender, jasmine, rose including rose water, ylang-ylang and a few others) get an amber, while their essential oils stay red. Benzyl alcohol, one of the EU’s original fragrance allergens, and the brightener kojic acid get an amber too, as does royal jelly (bee-product allergies cross over), and the preservative chlorphenesin gets a mild amber for rare allergy and irritation. In Malassezia mode, horse oil (horse fat, the Korean mayu cream) is flagged as an animal fat. Parabens, on the other hand, were named the society’s (non)allergen of the year, so their note says they’re one of the gentlest preservatives. Chilli extract (capsaicin or capsicum, often in lip plumpers) gets an amber too, because it switches on the same heat receptor that makes spicy food flush. Newer cooling agents (menthoxypropanediol, menthone glycerin acetal and the “menthane” coolers) get an amber as well, since they work on the same cold receptor as menthol. Vanillyl butyl ether, the warming agent in some lip plumpers and “hot” masks, gets an amber for the same reason as chilli. Sponge spicules (listed as hydrolyzed sponge, the VT Reedle Shot trend) get the same red as scrubbing grains, because they’re tiny needles made to prick the skin.
Pore-clogging (comedogenic) ingredients
For pore clogging, red means the ingredient was named as an offender in rabbit ear studies by dermatologist James Fulton and colleagues, mostly esters like isopropyl myristate, isopropyl palmitate and ethylhexyl palmitate, plus cocoa butter and acetylated lanolin. Amber covers oils like coconut, wheat germ and apricot kernel that showed up in the early tests but have less behind them. These ratings come from rabbit ears, which Fulton himself called not an ideal model, and a finished product can behave differently to a single ingredient. So treat this mode as a rough guide, not a verdict. Cocoa butter is the one with human studies behind it as well, though they disagree: one found it clogged pores, another found the effect weak.
The green flags in this mode come from the American Academy of Dermatology’s 2024 acne guidelines. Retinoids (adapalene, tretinoin, tazarotene) and benzoyl peroxide get a strong recommendation there, and salicylic acid and azelaic acid a conditional one, which means the evidence is thinner. It also picks out the prescription ones: the antibiotics clindamycin and erythromycin (strongly recommended) and clascoterone (conditional). Dapsone gel gets one as well, from two trials in over 4,000 people, and so does minocycline foam. Spironolactone gel, green tea, bakuchiol and retinal (tested mixed with glycolic acid) get mild ones. So do aloe vera (as an add-on to tretinoin), resveratrol (one small split-face pilot) and sulfur (older trials, mostly mixed with sulfacetamide). Isotretinoin gel and nadifloxacin, both prescription creams in the UK and Europe, get full greens, and so does lincomycin gel. Linoleic acid gets a mild green from a small trial, and so does propolis (from a trial where it was mixed with tea tree oil and aloe). Gluconolactone gets a full green after matching benzoyl peroxide in a 150-person trial, while glycolic acid, lactic acid and zinc (not zinc oxide) get mild greens because their evidence is weaker. There’s also a grey “Tested, did not clog” note for around 70 everyday ingredients that scored 0 or 1 in Fulton’s rabbit ear study (glycerin, polysorbates, PEG-100 stearate, plain glyceryl stearate, kaolin, carbomer and more), so a moisturiser full of them shows you what was actually tested instead of staying blank. In Malassezia mode, azelaic acid gets a mild “may help” for facial seb derm, behind ketoconazole, and ingredients the 2019 Dobler lab study found the yeast can’t feed on (mineral oil, petrolatum, squalane, silicones, polymers and conditioning quats) now show “Tested, no malassezia growth”. Anything the checker recognises but has nothing to say about in a tab, like water, pH adjusters, gentle preservatives and pigments, is listed under “Known, nothing to flag here”, so a blank result never means the checker didn’t read it. On the caution side, the oils Fulton rated 3 out of 5 (sesame, corn, avocado, evening primrose, mink, soybean, shark liver and cottonseed) get an amber, as do oleic acid and the four red dyes that scored 3 in Fulton’s study (D&C Reds 3, 17, 30 and 36; the other reds scored 1 or 2 and aren’t flagged).
Fulton’s 1989 follow-up paper adds a few more to the watch list. Laureth-4 goes red, because he named it as a major offender alongside isopropyl myristate and acetylated lanolin alcohol. Lauric acid and the pigment D and C Red 36 get an amber, since how much they clogged pores depended on what they were mixed with. Later sources list more pore-cloggers from that same 1989 survey (algae extract, myristyl lactate, oleyl alcohol, isocetyl alcohol, oleth-3 and a few others). Those get an amber too, because I couldn’t check the original ratings myself. The 2024 acne guidelines found the evidence for plant extracts, vitamins and chemical peels wasn’t enough to make a recommendation either way. Two of those still get a mild green from small trials of their own: niacinamide, which did about as well as an antibiotic gel, and tea tree oil, which beat a placebo gel.
Anti-ageing ingredients
Anti-ageing mode works the other way round and grades the ingredients that have research behind them for wrinkles, collagen and sun damage. There’s also a grey “Lab or animal only” grade, because loads of K-beauty favourites (mugwort, heartleaf, yuja, mung bean, lotus, birch sap and Korean camellia) have only been tested on skin cells or in the lab so far. That doesn’t mean they don’t work, just that nobody has checked on real faces yet. Red pine, peony, tremella, rice and soy extract get an early grade from small human studies, and the dark spot fighters are graded for pigment rather than wrinkles. Hydroquinone (prescription-only in the UK) and azelaic acid have the strongest evidence, tranexamic acid, Thiamidol, Melasyl and cysteamine have some, and alpha-arbutin, kojic acid, licorice, mulberry and N-acetyl glucosamine are early. You don’t have to paste the label, either. Type everyday names like vitamin C, cica, snail mucin, salmon DNA, copper peptides or Differin, and the checker translates them into the ingredient name on the label.
Strong evidence goes to prescription retinoids like tretinoin, and to sunscreen filters, because a 4.5-year trial found people who wore sunscreen daily showed no detectable increase in skin ageing. Some evidence covers retinol, retinal, pure vitamin C, niacinamide, glycolic acid, lactic acid, alpha lipoic acid, acetyl zingerone, progesterone cream, snail mucin, adenosine, Matrixyl (palmitoyl pentapeptide-4), DMAE, centella, resveratrol and retinyl retinoate (a newer Korean retinoid that beat retinol in a small trial) and oleyl adapalenate (Adapinoid, a gentler adapalene that also beat retinol), which each have at least one human trial. Early goes to bakuchiol, HPR (hydroxypinacolone retinoate, only tested in blends so far), idebenone, methyl estradiolpropanoate (the skin-only oestrogen in some menopause skincare), peptides, retinyl esters like retinyl palmitate, growth factors (EGF), vitamin K2, estriol and estradiol creams, hexylresorcinol, melatonin, PHAs like gluconolactone, madecassoside (from centella), green tea, boswellia, PDRN (salmon DNA), oat beta-glucan, rosehip oil (the famous trial was a supplement, not the oil), collagen creams (the research is on supplements), Argireline (the needle-free Botox peptide), vitamin E (mainly a moisturiser), CoQ10, genistein (soy isoflavone), copper peptide, astaxanthin (the research is mostly on supplements), caffeine (in eye trials the cool gel did most of the work), kinetin, ginseng (the trials were supplements), ectoin, coffeeberry (coffee fruit extract), mandelic acid, ferulic acid (mainly a vitamin C stabiliser), Galactomyces (Pitera), Pro-Xylane (L’Oreal’s in-house figures only), Acmella oleracea (natural Botox, and only temporary), exosomes (tiny studies so far), glutathione (one small split-face trial), bee venom, apple stem cells (maker data only), hyaluronic acid and vitamin C derivatives, where the studies are small or run by the people who make the ingredient.
Anything it doesn’t grade isn’t bad for your skin (it just hasn’t got anti-ageing research the checker knows about). And if you’ve got rosacea too, flip to that tab after, because retinoids and glycolic acid are both on the rosacea list.
Adapalene gets a “some evidence” too, because 0.3% did as well as tretinoin on sun-damaged skin in a 24-week trial. This tab doesn’t have a red list, and that’s on purpose. The thing with real proof behind it for ageing skin is the sun, which is why sunscreen gets a strong grade. I looked for skincare ingredients proven to break down collagen or age your face and couldn’t find any with solid human evidence, so I’d rather flag nothing than scare you off a product. The closest thing is a sun warning: the US FDA says acids like glycolic acid make skin more sensitive to the sun for up to a week, so that note sits on glycolic acid’s result.
Sensitive skin and eczema
These two tabs flag the ingredients most likely to cause a skin allergy or sting. Fragrance and essential oils get red, because fragrance is one of the most common causes of skin allergy (in a 2024 review of European allergy clinics, about 7 in 100 people tested reacted to the main fragrance test mix). Methylisothiazolinone gets red too, because the EU banned it from leave-on products after so many people reacted to it.
Amber covers the fragrance allergens brands have to name on the label, preservatives that let off tiny amounts of formaldehyde, lanolin, daisy family plants like chamomile and calendula, propylene glycol and sulfate cleansers. Most people get on fine with all of these. They’re on the list because if you do react to something, these are the usual suspects.
The eczema tab is a bit stricter. SLS goes red, because eczema skin got more damaged by it and took longer to bounce back in a 2015 study, and olive oil goes amber after it weakened the skin barrier in a 2013 study. It also has green flags for ceramides, colloidal oatmeal, urea and sunflower seed oil, which all have trials behind them.
You might notice cocamidopropyl betaine isn’t flagged. It’s a gentle cleanser that used to get blamed for a lot, but a study of over 80,000 patch tests found most reactions to it were false alarms, and real allergy to it is very rare.
Get the best result
Copy the list off the actual box if you can. Retailer pages and ingredient sites sometimes show an older formula, and I’ve found two different ingredient lists online for the same scalp serum, so the box wins every time.
Paste the whole thing and separate it however you like. Bits in brackets like Aqua (Water) stay together.
Using a few actives at once? My skincare routine checker tells you which products are fine together, which ones to split between morning and night, and whether you’ve doubled up on anything.
It can’t diagnose anything (it just reads labels). If your skin’s flaring and nothing seems to help, a GP or dermatologist is your best bet.
Ingredient checker questions
What do the colours mean?
Red is flagged, so that’s one to watch out for. Amber is worth watching (it might be fine for you, it might not). Green has research behind it. Grey means it was tested and came out fine, or it’s only been tried in a lab so far.
Is squalane fungal acne safe?
Squalane didn’t feed malassezia in the 2019 Dobler lab study, so the checker marks it “Tested, no malassezia growth”.
Is coconut oil fungal acne safe?
The checker flags it. Most plant oils are full of the fatty acids malassezia feeds on, and coconut oil is one of them.
Does it work for seb derm on the scalp?
Yes. Seb derm and fungal acne are driven by the same yeast, so the Malassezia tab works on shampoos, conditioners and scalp serums too. My hair growth ingredient checker has the same seb derm list built in.
Can it tell me if a product will break me out?
No, it just reads labels. A flag is only a heads up. Loads of people use flagged products and get on fine with them, so patch test and trust your own skin.
Sources the checker is built on
Every red, amber and green reason in the checker comes from one of these, or from the rules explained above. Tap the button to see them all, grouped by checker mode.
Show all 316 sources
Fungal acne and seb derm (Malassezia mode)
- Dobler D, Schmidts T, Wildenhain S, Seewald I, Merzhäuser M, Runkel F. Impact of Selected Cosmetic Ingredients on Common Microorganisms of Healthy Human Skin. Cosmetics, 2019 – the lab study behind the cetearyl alcohol, hydrogenated castor oil, lanolin and coco-caprylate/caprate results
- Clark GW, Pope SM, Jaboori KA. Diagnosis and Treatment of Seborrheic Dermatitis. American Family Physician, 2015 – ketoconazole, coal tar, tea tree oil, azoles, salicylic acid, sulfur and the prescription creams (the green “may help” flags)
- Borda LJ, Perper M, Keri JE. Seborrheic Dermatitis and Dandruff: A Comprehensive Review. Journal of Clinical and Investigative Dermatology, 2015 – piroctone olamine, zinc pyrithione and selenium sulfide
- A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis. Journal of Dermatological Treatment, 2002 – ciclopirox
- Okokon EO and colleagues. Topical antifungals for seborrhoeic dermatitis. Cochrane Database of Systematic Reviews, 2015 – lithium gluconate, including the 288-person trial against ketoconazole
- Diehl C, Ferrari A. Efficacy of topical 4% Quassia amara gel in facial seborrheic dermatitis: a randomized, double-blind, comparative study. Journal of Drugs in Dermatology, 2013 – Quassia amara
- Vardy DA and colleagues. A double-blind, placebo-controlled trial of an Aloe vera (A. barbadensis) emulsion in the treatment of seborrheic dermatitis. Journal of Dermatological Treatment, 1999 – aloe vera
- Al-Waili NS. Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. European Journal of Medical Research, 2001 – honey
- Faergemann J. Propylene glycol in the treatment of seborrheic dermatitis of the scalp: a double-blind study. Cutis, 1988 – propylene glycol
- Emtestam L, Svensson A, Rensfeldt K. Treatment of seborrhoeic dermatitis of the scalp with a topical solution of urea, lactic acid, and propylene glycol (K301): results of two double-blind, randomised, placebo-controlled studies. Mycoses, 2012 – propylene glycol in a scalp solution
- Zirwas MJ and colleagues. Efficacy of Roflumilast Foam, 0.3%, in Patients With Seborrheic Dermatitis: A Double-blind, Vehicle-Controlled Phase 2a Randomized Clinical Trial. JAMA Dermatology, 2023 – roflumilast
- Sepaskhah M, Shamshiri F, Bagheri Z. Comparison of the Effectiveness of Ivermectin 1% Cream and Ketoconazole 2% Cream in Treating Facial Seborrheic Dermatitis: A Double-Blind, Randomized, Controlled Clinical Trial. Health Science Reports, 2026 – ivermectin for seb derm
- Sadati MS and colleagues. Efficacy of Topical Rosemary Extract Lotion versus Topical 2% Ketoconazole Lotion in the Treatment of Seborrheic Dermatitis: A Double-Blind Randomized Controlled Clinical Trial. Dermatology Practical and Conceptual, 2024 – rosemary extract
- Chaijan MR and colleagues. The Myrtus communis L. solution versus ketoconazole shampoo in treatment of dandruff: a double blinded randomized clinical trial. Journal of the Pakistan Medical Association, 2018 – myrtle extract
- Mehta R and colleagues. A New Purpose to Old Arsenal: Exploring the Safety and Efficacy of a New Regimen Comprising a Combination of Chlorhexidine Gluconate and Cetrimide for Seborrheic Dermatitis Treatment in a Randomized Placebo-Controlled Clinical Trial. Cureus, 2024 – chlorhexidine
- Georgescu SR and colleagues. A Meta-Analysis on the Effectiveness of Sertaconazole 2% Cream Compared with Other Topical Therapies for Seborrheic Dermatitis. Journal of Personalized Medicine, 2022 – sertaconazole
- Abdel-Razek M and colleagues. Pityrosporum (Malassezia) folliculitis in Saudi Arabia: diagnosis and therapeutic trials. Clinical and Experimental Dermatology, 1995 – econazole and miconazole for fungal acne
- Sladowska K and colleagues. Efficacy and Safety of Epigallocatechin Gallate in the Treatment and Prevention of Dermatitis: A Systematic Review. Biomedicines, 2025 – green tea (EGCG) shampoo for scalp seb derm
- Dr Leslie Baumann, Skin Type Solutions: Yeast in Skin Care Products, Good or Bad? – why ferments get a caution rather than a red flag
- Papavassilis C, Mach KK, Mayser PA. Medium-chain triglycerides inhibit growth of Malassezia: Implications for prevention of systemic infection. Critical Care Medicine, 1999 – MCT oil
- Koyama T, Kanbe T, Kikuchi A, Tomita Y. Effects of topical vehicles on growth of the lipophilic Malassezia species. Journal of Dermatological Science, 2002 – petrolatum
- Mayser P and colleagues. Differentiation of Malassezia species: selectivity of cremophor EL, castor oil and ricinoleic acid for M. furfur. British Journal of Dermatology, 1997 – castor oil
- Gueniche A and colleagues. Vitreoscilla filiformis biomass improves seborrheic dermatitis. Journal of the European Academy of Dermatology and Venereology, 2008 – Vitreoscilla ferment
- Seckin D and colleagues. Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study. JEADV, 2007 – metronidazole for seb derm
- Is topical metronidazole effective in seborrheic dermatitis? A double-blind study (PubMed) – the metronidazole trial that found no difference from placebo
- Efficiency of terbinafine 1% cream in comparison with ketoconazole 2% cream and placebo in patients with facial seborrheic dermatitis, 2013 (PubMed) – terbinafine cream
- Status Report on Topical Hypochlorous Acid: Clinical Relevance of Specific Formulations, Potential Modes of Action, and Study Outcomes. Journal of Clinical and Aesthetic Dermatology, 2018 – hypochlorous acid
- Wang HC and colleagues. Evaluation of a new-formula shampoo containing 6% glycyrrhetinic acid complex for scalp seborrheic dermatitis: a pilot study. Journal of Cosmetic Dermatology, 2021 – glycyrrhetinic acid for seb derm
- Acibadem: Beef Tallow for Skin, Dermatology Weighs In on the Trend – beef tallow
- Tressless: neem hair and scalp research summary – neem leaf and neem oil
- Chaisripipat W, Lourith N, Kanlayavattanakul M. Anti-dandruff Hair Tonic Containing Lemongrass (Cymbopogon flexuosus) Oil. Forschende Komplementarmedizin, 2015 – lemongrass oil
- Wilde PF, Stewart PS. A study of the fatty acid metabolism of the yeast Pityrosporum ovale. Biochemical Journal, 1968 – the original finding that the yeast feeds on fatty acids roughly C11 to C24 long
- Nazzaro-Porro M, Passi S, Caprilli F, Nazzaro P, Morpurgo G. Growth requirements and lipid metabolism of Pityrosporum orbiculare. Journal of Investigative Dermatology, 1976 – the C12 to C24 growth range, and why short chains like caprylic acid do not feed it
- Mayser P, Führer D, Schmidt R, Gründer K. Hydrolysis of fatty acid esters by Malassezia furfur: different utilization depending on alcohol moiety. Acta Dermato-Venereologica, 1995 – why esters get flagged (the yeast splits them to reach the fatty acid inside)
- Mayser P and colleagues. Different utilization of neutral lipids by Malassezia furfur and Malassezia sympodialis. Medical Mycology, 1998 – olive oil and other plant oil triglycerides being broken down into free fatty acids
- Gaitanis G, Magiatis P, Hantschke M, Bassukas ID, Velegraki A. The Malassezia genus in skin and systemic diseases. Clinical Microbiology Reviews, 2012 – the big review behind the fatty acid rule, and heat, sweat and humidity as triggers
- Henning MAS and colleagues. Position statement: Recommendations on the diagnosis and treatment of Malassezia folliculitis. Journal of the European Academy of Dermatology and Venereology, 2023 – the European dermatology guidance on diagnosis and antifungal treatment
- Xu J and colleagues. Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens. PNAS, 2007 – why the yeast cannot make its own fatty acids and has to take them from skin and products
- Triana S and colleagues. Lipid metabolic versatility in Malassezia spp. yeasts studied through metabolic modeling. Frontiers in Microbiology, 2017 – lipid dependence, and why lab dish results do not always match real skin
- Juntachai W, Oura T, Murayama SY, Kajiwara S. The lipolytic enzymes activities of Malassezia species. Medical Mycology, 2009 – the enzymes the yeast uses to break down oils and esters
- Park M, Park S, Jung WH. Skin commensal fungus Malassezia and its lipases. Journal of Microbiology and Biotechnology, 2021 – lipases and how sebum and product lipids become yeast food
- Liebregts J and colleagues. Lipid-dependent growth of Malassezia spp. in defined medium with single fatty acids. FEMS Yeast Research, 2025 – palmitic and oleic acid as the strongest growth fuel, and species differences
- Chalupczak NV and colleagues. Malassezia Folliculitis: An Underdiagnosed Mimicker of Acneiform Eruptions. Journal of Fungi, 2025 – an up-to-date review of fungal acne, how it is diagnosed and treated
- Draelos ZD and colleagues. Malassezia Folliculitis Presentation, Diagnosis, and Treatment: A Review of “Fungal Acne”. Journal of Drugs in Dermatology, 2026 – the newest expert review of fungal acne, how it shows up and how it is treated
- Plotkin L and colleagues. Characterization of the lipase activity of Malassezia furfur. Journal of Medical and Veterinary Mycology, 1996 – polysorbate 80 (Tween 80) switching on the yeast’s lipase and growth at low amounts
- Malassezia restricta-mediated lipoperoxidation: a novel trigger in dandruff. Acta Dermato-Venereologica, 2023 – the yeast turning squalene into squalene peroxide
- Mayser P. Medium chain fatty acid ethyl esters: activation of antimicrobial effects by Malassezia enzymes. Mycoses, 2015 – why short-chain (C8 and C10) fats hold the yeast back instead of feeding it
- Guého E, Midgley G, Guillot J. The genus Malassezia with description of four new species. Antonie van Leeuwenhoek, 1996 – the standard lab tests for which Malassezia species can use polysorbates (Tweens) as food
- Gordon James A and colleagues. Metabolic analysis of the cutaneous fungi Malassezia globosa and M. restricta for insights on scalp condition and dandruff. International Journal of Cosmetic Science, 2013 – why some species can use oleic acid and others cannot
- Draelos ZD and colleagues. Malassezia folliculitis presentation, diagnosis, and treatment: a review of “fungal acne”. Journal of Drugs in Dermatology, 2026 – the newest dermatology review of fungal acne
- Cabrera Díaz CE and colleagues. Malassezia lipidome: the dynamics of uptake and secreted lipids. Virulence, 2026 – which lipids the yeast takes up as it grows, including sterols
- Akaza N and colleagues. Malassezia globosa tends to grow actively in summer conditions more than other cutaneous Malassezia species. Journal of Dermatology, 2012 – sweat, heat and free fatty acids boosting the main fungal acne species
- Saadatzadeh MR, Ashbee HR, Holland KT, Ingham E. Production of the mycelial phase of Malassezia in vitro. Medical Mycology, 2001 – the lipids (including glyceryl stearate, Tween 80 and squalene) used to push the yeast into its problem-causing form
- Nazzaro-Porro M and colleagues. Induction of hyphae in cultures of Pityrosporum by cholesterol and cholesterol esters. Journal of Investigative Dermatology, 1977 – cholesterol mixed with fatty esters and the yeast’s growth
- Nenoff P, Haustein UF. In vitro activity of phytosphingosines against Malassezia furfur and Candida albicans. Acta Dermato-Venereologica, 2002 – phytosphingosine held the yeast back only at very high amounts and boosted it at low amounts
- Caprilli F and colleagues. Studies of the genus Pityrosporum in submerged culture. Mycopathologia et Mycologia Applicata, 1973 – early study of what the yeast needs to grow
- Saint-Leger D and colleagues. A possible role for squalene in the pathogenesis of acne. I. In vitro study of squalene oxidation. British Journal of Dermatology, 1986 – how oxidised squalene may clog pores
- Exploration of scalp surface lipids reveals squalene peroxide as a potential actor in dandruff condition. Archives of Dermatological Research, 2016 – squalene peroxide on scalps with dandruff
- Harding CR and colleagues. Dandruff: a condition characterized by decreased levels of intercellular lipids in scalp stratum corneum and impaired barrier function. Archives of Dermatological Research, 2002 – the scalp barrier and ceramide changes in dandruff
- Kim SK, Karadeniz F. Biological importance and applications of squalene and squalane. Advances in Food and Nutrition Research, 2012 – the difference between squalene and squalane
- Saunders CW, Scheynius A, Heitman J. Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases. PLoS Pathogens, 2012 – why the yeast depends on skin oils
- Kim GK. Seborrheic dermatitis and Malassezia species: how are they related? Journal of Clinical and Aesthetic Dermatology, 2009 – the link between seb derm and the yeast
- Improved detection of Malassezia species in lipid-supplemented Peds Plus blood culture bottles. Journal of Clinical Microbiology, 1995 – palmitic and oleic acid as strong growth fuel
- Kaushik N, Vir S. Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. Biochemical Society Transactions, 2000 – why neem oil gets flagged (mostly palmitic, stearic, oleic and linoleic acid)
- Gupta AK, Nicol K, Batra R. Role of antifungal agents in the treatment of seborrheic dermatitis. American Journal of Clinical Dermatology, 2004 – antifungals, tea tree oil, honey and cinnamic acid against the yeast
- Brasch J, Christophers E. Azelaic acid has antimycotic properties in vitro. Dermatology, 1993 – azelaic acid holding the yeast back
- DermNet: Malassezia folliculitis – a dermatologist-written overview of fungal acne
- Ashbee HR, Evans EGV. Immunology of diseases associated with Malassezia species. Clinical Microbiology Reviews, 2002 – a major review of how the yeast affects skin, one of the papers Sezia’s checker is built on
- Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner. Clinical and Experimental Dermatology, 2015 – galactomyces switching on the same skin receptor the yeast does, behind the caution on ferments
- Rubenstein RM, Malerich SA. Malassezia (Pityrosporum) folliculitis. Journal of Clinical and Aesthetic Dermatology, 2014 – a dermatology review of fungal acne, including the fatty acids the yeast needs to grow
- PubChem (US National Library of Medicine) – used to confirm the chemical structure and chain length of flagged ingredients
- Cosmetic Ingredient Review (CIR) – the US expert panel that reviews whether cosmetic ingredients are safe to use. It judges general safety, not whether an ingredient feeds the yeast
- European Commission: CosIng cosmetic ingredient database – used to check the chemical name and fatty chain length of every ingredient the checker flags, and to find oil-derived esters, soaps and fatty alcohols it was missing
- Martínez-Ortega J, Mut Quej JE, Franco González S. Malassezia folliculitis: Pathogenesis and diagnostic challenges. Cureus, 2024 – what fungal acne looks like (small, itchy, same-size bumps) and how it is diagnosed
- Rhimi W, Theelen B, Boekhout T, Otranto D, Cafarchia C. Malassezia spp. yeasts of emerging concern in fungemia. Frontiers in Cellular and Infection Microbiology, 2020 – background on the main Malassezia species
- Glatz M, Bosshard PP, Hoetzenecker W, Schmid-Grendelmeier P. The role of Malassezia spp. in atopic dermatitis. Journal of Clinical Medicine, 2015 – Malassezia, eczema and the skin barrier
- Sparber F, LeibundGut-Landmann S. Host responses to Malassezia spp. in the mammalian skin. Frontiers in Immunology, 2017 – how the immune system reacts to the yeast
- Saunte DML, Gaitanis G, Hay RJ. Malassezia-associated skin diseases, the use of diagnostics and treatment. Frontiers in Cellular and Infection Microbiology, 2020 – the skin conditions linked to Malassezia and how they are treated
- Sanders MGH, Pardo LM, Franco OH, Ginger RS, Nijsten T. Prevalence and determinants of seborrhoeic dermatitis in a middle-aged and elderly population: the Rotterdam Study. British Journal of Dermatology, 2018 – how common seb derm is and who gets it
Rosacea
- National Rosacea Society: Ingredients May Aggravate Rosacea – alcohol, witch hazel, fragrance, menthol, peppermint and eucalyptus oil
- National Rosacea Society: Rosacea Awareness Month Calls for Holistic Approach (2025) – the 2025 survey figures for fragrance, dyes, sulfates and parabens or other preservatives
- National Rosacea Society: Rosacea Skin Care and Cosmetics – exfoliating agents, harsh products, and the American Academy of Dermatology on fragrance allergy
- American Academy of Dermatology: 7 Rosacea Skin Care Tips Dermatologists Recommend – alcohol, camphor, fragrance, glycolic and lactic acid, menthol, sodium lauryl sulfate and urea
- American Academy of Dermatology: Rosacea Diagnosis and Treatment – benzoyl peroxide on sensitive skin
- American Academy of Dermatology: Acne Diagnosis and Treatment – retinoid side effects and how to reduce them
- EU Commission Regulation 2016/1198 – the ban on methylisothiazolinone in leave-on cosmetics
- Dr Leslie Baumann, Skin Type Solutions: Best Vitamin C Serums for Rosacea – why acidic L-ascorbic acid can irritate rosacea-prone skin
- Rosacea: Diagnosis and Treatment. American Family Physician, 2015 – azelaic acid, metronidazole, sulfur, permethrin, ceramides and PHAs (green flags), plus acetone, abrasives, astringents, niacin and topical steroids (avoid list)
- National Rosacea Society: FDA Approved Treatments for Rosacea – azelaic acid, ivermectin, brimonidine and oxymetazoline
- Draelos ZD, Ertel K, Berge C. Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. Cutis, 2005 – niacinamide
- A two-center randomized controlled trial of a repairing mask as an adjunctive treatment for mild to moderate rosacea. Journal of Cosmetic Dermatology, 2024 – centella (madecassoside, cica)
- Proksch E, Nissen HP. Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation. Journal of Dermatological Treatment, 2002 – panthenol
- Gueniche A and colleagues. Bifidobacterium longum lysate, a new ingredient for reactive skin. Experimental Dermatology, 2010 – Bifida ferment lysate
- Green tea in dermatology. Skinmed, 2012 – green tea
- Randomized placebo-controlled trial of a flavonoid-rich plant extract-based cream in the treatment of rosacea. Journal of the European Academy of Dermatology and Venereology, 2005 – Chrysanthellum indicum
- Weber TM and colleagues. Skin tolerance, efficacy, and quality of life of patients with red facial skin using a skin care regimen containing Licochalcone A. Journal of Cosmetic Dermatology, 2006 – licochalcone A
- Cameli N, Mariano M, Zanniello R, Berardesca E. Clinical and non-invasive instrumental evaluation of the efficacy of a non-steroid anti-inflammatory 18-beta glycyrrhetinic acid cream for the treatment of erythema in rosacea. Dermatologic Therapy, 2020 – glycyrrhetinic acid
- Berardesca E and colleagues. Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation. Journal of Cosmetic Dermatology, 2008 – milk thistle (silymarin) and MSM
- Bageorgou F and colleagues. The new therapeutic choice of tranexamic acid solution in treatment of erythematotelangiectatic rosacea. Journal of Cosmetic Dermatology, 2019 – tranexamic acid
- Ferrari A, Diehl C. Evaluation of the efficacy and tolerance of a topical gel with 4% Quassia extract in the treatment of rosacea. Journal of Clinical Pharmacology, 2012 – Quassia amara
- Jovanovic Z and colleagues. Efficacy and tolerability of a cosmetic skin care product with trans-4-t-butylcyclohexanol and licochalcone A in subjects with sensitive skin prone to redness and rosacea. Journal of Drugs in Dermatology, 2017 – 4-t-butylcyclohexanol
- Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clinical and Experimental Dermatology, 2007 – kinetin
- Kim TW and colleagues. Topical application of Scutellaria baicalensis suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis. Natural Product Research, 2016 – Scutellaria baicalensis (mouse study)
- Yun C and colleagues. Anti-Inflammatory Effects of Artemisia Leaf Extract in Mice with Contact Dermatitis In Vitro and In Vivo. Mediators of Inflammation, 2016 – mugwort (mouse and cell study)
- Huang R and colleagues. Houttuynia cordata polysaccharides ameliorate atopic dermatitis in mice through modulation of skin immune barrier and lipid metabolism. International Journal of Biological Macromolecules, 2025 – heartleaf (mouse study)
- Stein Gold L and colleagues. Minocycline 1.5% foam for the topical treatment of moderate to severe papulopustular rosacea: Results of 2 phase 3, randomized, clinical trials. Journal of the American Academy of Dermatology, 2020 – minocycline
- Bhatia ND and colleagues. Efficacy and Safety of Microencapsulated Benzoyl Peroxide Cream, 5%, in Rosacea: Results From Two Phase III, Randomized, Vehicle-Controlled Trials. Journal of Clinical and Aesthetic Dermatology, 2023 – encapsulated benzoyl peroxide
- Braithwaite I and colleagues. Randomised controlled trial of topical kanuka honey for the treatment of rosacea. BMJ Open, 2015 – honey
- Draelos ZD. Efficacy, Tolerance, and Safety of a Novel Botanical Anti-Inflammatory Moisturizer in Rosacea: Results From a Double-Blinded, Randomized Controlled Trial. Journal of Cosmetic Dermatology, 2026 – oat and aloe
- Wei D, Hamblin MR, Wen X. A randomized, controlled, split-face study of topical timolol maleate 0.5% eye drops for the treatment of erythematotelangiectatic rosacea. Journal of Cosmetic Dermatology, 2021 – timolol
- Kocak M, Yagli S, Vahapoglu G, Eksioglu M. Permethrin 5% cream versus metronidazole 0.75% gel for the treatment of papulopustular rosacea. A randomized double-blind placebo-controlled study. Dermatology, 2002 – permethrin
- Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems. Molecular Pharmaceutics, 2023 – capsaicin and the heat receptor behind flushing
- Altmeyer’s Encyclopedia, Department of Dermatology: Menthoxypropanediol – cooling agents and the menthol receptor
- Miyazawa and colleagues. Allergic contact dermatitis caused by menthoxypropanediol in a skin care lotion. Contact Dermatitis, 2024 – allergy reports to cooling agents
- Dermatology Times: Lanolin Named Allergen of the Year (2023) – lanolin
- Propylene Glycol in Contact Dermatitis: A Systematic Review. Dermatitis, 2018 – propylene glycol
- The Dermatologist: Allergen of the Year by the American Contact Dermatitis Society – glucoside cleansers and the full list
- MDedge: Benzophenones named 2014 Contact Allergen of the Year – benzophenone sunscreen filters
- Ekstein SF, Warshaw EM. Sulfites: Allergen of the Year 2024. Dermatitis, 2024 – sulfites
- Allergen of the Year (list, including parabens as the 2019 non-allergen) – parabens
- Commission Regulation (EU) 2017/1410 – oakmoss, treemoss and HICC
- Coslaw: More allergens to be individually labelled, EU Regulation 2023/1545 – the 2023 fragrance allergen additions
- GBA Polska: Fragrance allergen labelling requirements in cosmetics after the changes – the full list of new pure-substance allergens
- Warshaw EM and colleagues. Positive patch-test reactions to iodopropynyl butylcarbamate: North American Contact Dermatitis Group data, 1998 to 2008. Dermatitis, 2010 – IPBC
- DermNet: Benzalkonium chloride contact dermatitis – benzalkonium chloride
- DermNet: Compositae allergy – the daisy family plants
- Jovanovic M and colleagues. Contact allergy to Compositae plants in patients with atopic dermatitis. Medicinski Pregled, 2004 – the 30% daisy family reaction rate
- DermNet: Rosin (colophony) allergy – colophony
- Holcomb ZE, Van Noord MG, Atwater AR. Gallate Contact Dermatitis: Product Update and Systematic Review. Dermatitis, 2017 – gallates
- Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide. Contact Dermatitis, 2014 – cocamide DEA
- “Shampoo” Distribution of Allergic Contact Dermatitis – amidoamines
- Watkins S, Zippin J. Allergic Contact Dermatitis and Cosmetics. Cutis, 2017 – shellac
- Bennike NH, Johansen JD. Sorbitan sesquioleate; a rare cause of contact allergy. Contact Dermatitis, 2016 – sorbitan sesquioleate
- A European multicentre photopatch test study. British Journal of Dermatology, 2012 – octocrylene and avobenzone
- Aerts O, Verhulst L, Goossens A. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in hypo-allergenic cosmetics. Contact Dermatitis, 2016 – ethylhexylglycerin
- Cosmetics and Toiletries: Vanillyl Butyl Ether to Topically Induce Blood Cell Flux, Warming Sensation – vanillyl butyl ether
- Chemist Confessions: Reedle Shot Deep Dive, Science of Spicules in Skincare – sponge spicules and redness
- Facial tolerance of a feverfew-PFE-containing daily moisturizer regimen in mild to moderate rosacea patients. Journal of the American Academy of Dermatology, 2008 – feverfew
- Berardesca E and colleagues. Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea. Journal of Cosmetic Dermatology, 2012 – potassium azeloyl diglycinate
- Schlesinger TE, Powell CR. Efficacy and tolerability of low molecular weight hyaluronic acid sodium salt 0.2% cream in rosacea. Journal of Drugs in Dermatology, 2013 – hyaluronic acid
- Ozbagcivan O and colleagues. Contact sensitization to cosmetic series of allergens in patients with rosacea: A prospective controlled study. Journal of Cosmetic Dermatology, 2019 – gallates, BHT, TBHQ, methyldibromo glutaronitrile and cocamidopropyl betaine
- Chen B and colleagues. Contact sensitization to cosmetic series of allergens in female patients with rosacea: A prospective controlled study in China. Journal of Cosmetic Dermatology, 2020 – formaldehyde releasers, propolis and balsam of Peru
- Jappe U and colleagues. Contact allergy in patients with rosacea: a clinic-based, prospective epidemiological study. Journal of the European Academy of Dermatology and Venereology, 2008 – balsam of Peru
Pore clogging
- Fulton JE Jr, Pay SR, Fulton JE 3rd. Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear. J Am Acad Dermatol, 1984 – the named pore-clogging esters
- Frank SB. Is the rabbit ear model, in its present state, prophetic of acnegenicity? Journal of the American Academy of Dermatology, 1982 – why rabbit ear ratings do not line up well with human skin
- Mills OH, Kligman AM. A human model for assessing comedogenic substances. Archives of Dermatology, 1982 – the human test, which found the rabbit ear is more sensitive than people are
- Draelos ZD, DiNardo JC. A re-evaluation of the comedogenicity concept. Journal of the American Academy of Dermatology, 2006 – finished products with “pore clogging” ingredients are not always pore clogging, which is why these flags are amber, not red
- Weiss C, Caswell M. Non-comedogenic and non-acnegenic claim substantiation. Journal of Cosmetic Science, 2017 – how brands test a non-comedogenic claim
- Boozalis E, Patel S. Clinical utility of marketing terms used for over-the-counter dermatologic products. Journal of Dermatological Treatment, 2018 – “non-comedogenic” and “oil-free” on a label are not regulated by anyone
- Kligman AM, Kwong T. An improved rabbit ear model for assessing comedogenic substances. British Journal of Dermatology, 1979 – how the rabbit ear pore clogging test works
- Morris WE, Kwan SC. Use of the rabbit ear model in evaluating the comedogenic potential of cosmetic raw materials. Journal of the Society of Cosmetic Chemists – early rabbit ear ratings for cosmetic ingredients
- Kligman AM and colleagues. Petrolatum is not comedogenic in rabbits or humans: a critical reappraisal of the rabbit ear assay and the concept of “acne cosmetica” – why petrolatum is rated 0
- Mirshahpanah P, Maibach HI. Models in acnegenesis. Cutaneous and Ocular Toxicology, 2007 – the rabbit ear test overreacts and is only reliable for ruling ingredients out
- Chularojanamontri L and colleagues. Moisturizers for acne: what are their constituents? Journal of Clinical and Aesthetic Dermatology, 2014 – which moisturiser ingredients suit acne-prone skin
- Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: a double-blind randomized controlled trial, 2021 – a human trial testing products for pore clogging
- ClinicalTrials.gov NCT03428997: Human Comedogenicity Test (Johnson and Johnson), completed 2018 – a human patch test for pore clogging
- American Academy of Dermatology: How to test skin care products – how to patch test a new product before using it all over
- Comedogenicity in rabbit: some cosmetic ingredients/vehicles (PubMed) – cocoa butter and the esters that tested positive, and cetyl alcohol, stearyl alcohol and petrolatum, which did not
- JAAD Reviews: Comedogenicity in cosmeceuticals, a review of clinical relevance, 2025 – coconut, wheat germ and apricot kernel oils, acetylated lanolin, and the history of the rating scale
- Reynolds RV, Barbieri JS and colleagues. Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 2024 – retinoids, benzoyl peroxide, topical antibiotics, clascoterone, salicylic acid and azelaic acid (the green flags)
- Fulton JE Jr. Comedogenicity and irritancy of commonly used ingredients in skin care products. Journal of the Society of Cosmetic Chemists, 1989 – laureth-4, lauric acid and D and C Red 36
- Women’s Concepts: Comedogenic and Pore-Clogging Ingredients (a list taken from Fulton’s 1989 paper) – the extra 1989 ambers, second-hand
- Shalita AR and colleagues. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. International Journal of Dermatology, 1995 – niacinamide
- Shahmoradi Z and colleagues. Comparison of topical 5% nicotinamid gel versus 2% clindamycin gel in the treatment of the mild-moderate acne vulgaris: a double-blinded randomized clinical trial. Journal of Research in Medical Sciences, 2013 – niacinamide
- Enshaieh S and colleagues. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian Journal of Dermatology, Venereology and Leprology, 2007 – tea tree oil
- Thiboutot DM and colleagues. Efficacy, Safety, and Dermal Tolerability of Dapsone Gel, 7.5% in Patients with Moderate Acne Vulgaris: A Pooled Analysis of Two Phase 3 Trials. Journal of Clinical and Aesthetic Dermatology, 2016 – dapsone
- Stein Gold L and colleagues. A novel topical minocycline foam for the treatment of moderate-to-severe acne vulgaris: Results of 2 randomized, double-blind, phase 3 studies. Journal of the American Academy of Dermatology, 2019 – minocycline for acne
- Baek JH and colleagues. Early detection of microcomedones induced by cocoa butter using reflectance confocal microscopy. Journal of Cosmetic Dermatology, 2021 – cocoa butter on human skin
- Lee E, Kim N, Jung A, Ha J. Isopropyl Myristate and Cocoa Butter are not Appropriate Positive Controls for Comedogenicity Assay in Asian Subjects, 2015 – cocoa butter and isopropyl myristate on human skin
- Afzali BM and colleagues. Comparison of the efficacy of 5% topical spironolactone gel and placebo in the treatment of mild and moderate acne vulgaris: a randomized controlled trial. Journal of Dermatological Treatment, 2012 – spironolactone gel
- The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials. Phytotherapy Research, 2020 – green tea for spots
- Applications of bakuchiol in dermatology: Systematic review of the literature. Journal of Cosmetic Dermatology, 2022 – bakuchiol for spots
- Poli F and colleagues. Efficacy and safety of 0.1% retinaldehyde/6% glycolic acid (Diacneal) for mild to moderate acne vulgaris: a multicentre, double-blind, randomized, vehicle-controlled trial. Dermatology, 2005 – retinal for spots
- Zhong H and colleagues. Efficacy of a New Non-drug Acne Therapy: Aloe Vera Gel Combined With Ultrasound and Soft Mask. Frontiers in Medicine, 2021 – aloe vera for spots, including the aloe and tretinoin trial
- Resveratrol-Containing Gel for Acne. Journal of Drugs in Dermatology, 2011 – resveratrol for spots
- The Use of Sodium Sulfacetamide in Dermatology. Cutis – sulfur for spots
- Chalker DK, Lesher JL, Smith JG. Efficacy of topical isotretinoin 0.05% gel in acne vulgaris. JAAD, 1987 – isotretinoin gel
- Nadifloxacin, including Plewig and colleagues’ phase III comparison with erythromycin, 2006 – nadifloxacin
- Letawe C and colleagues. Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. Clinical and Experimental Dermatology, 1998 – linoleic acid
- Sharma AD and colleagues. Topical lincomycin gel in acne vulgaris: a multicentric placebo controlled study. Indian Journal of Dermatology, Venereology and Leprology, 2003 – lincomycin
- Fulton JE. Comedogenicity and irritancy of commonly used ingredients in skin care products, Table I. Journal of the Society of Cosmetic Chemists, 1989 – the oils rated 3, oleic acid and D&C red dyes
- European Commission: Fragrance allergies, the 26 labelled allergens – benzyl alcohol
- Allergic Contact Dermatitis to Kojic Acid. Actas Dermo-Sifiliograficas – kojic acid
- Ebrahimi B, Naeini FF. Topical tranexamic acid as a promising treatment for melasma. Journal of Research in Medical Sciences, 2014 – tranexamic acid
- Glico: alpha-arbutin clinical and lab study summary – alpha-arbutin
- Wallo W, Nebus J, Leyden JJ. Efficacy of a soy moisturizer in photoaging: a double-blind, vehicle-controlled, 12-week study. Journal of Drugs in Dermatology, 2007 – soy extract
- Protective effect of partially purified paeoniflorin and anti-wrinkle clinical trial. Journal of Cosmetic Science, 2006 – peony
- Kim EJ and colleagues (Amorepacific). The anti-aging effects of cosmetic products containing the needles of red pine on human skin. Korea Journal of Herbology, 2006 – red pine
- Moisturizing efficacy of polysaccharides from white jelly mushroom (Tremella fuciformis). Mae Fah Luang University, 2024 – tremella
- Marto J and colleagues. Rice water: a traditional ingredient with anti-aging efficacy. Cosmetics, 2018 – rice
- Kim K, Sohn Y, Yeon JH. Anti-ageing activities of nanovesicles derived from Artemisia princeps in human dermal cells and human skin model. 2025 – mugwort
- Mapoung S and colleagues. Photoprotective effects of a hyperoside-enriched fraction from Houttuynia cordata on UVB-induced skin aging in human fibroblasts. Plants, 2021 – heartleaf
- Jung YY and colleagues. Skin improvement with antioxidant effect of Yuja (Citrus junos) peel fractions. Antioxidants, 2022 – yuja
- Studies on multi-functional cosmetics activities of peptide hydrolysates from cultured plant cells of Vigna radiata. Ajou University, 2015 – mung bean
- Nutho B, Tungmunnithum D. Exploring major flavonoid phytochemicals from Nelumbo nucifera as potential skin anti-aging agents. International Journal of Molecular Sciences, 2023 – lotus
- Moriyama M and colleagues. Effect of birch sap on cultured human epidermal keratinocyte differentiation. Journal of Society of Cosmetic Chemists of Japan, 2008 – birch sap
- Screening of Korean plant extracts for anti-aging cosmetic ingredients. Journal of Cosmetic Science, 2007 – Korean camellia
- Mazzarello V and colleagues. Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream. Clinical Pharmacology: Advances and Applications, 2018 – propolis
- Hata T and colleagues. Studies of royal jelly and associated cross-reactive allergens in atopic dermatitis patients. PLOS One, 2020 – royal jelly
- Separation and analysis of fatty acids from horse fat. Chemistry and Chemical Engineering, 2025 – horse fat
- Topical treatments for melasma and their mechanism of action. Journal of Clinical and Aesthetic Dermatology, 2022 – hydroquinone
- Efficacy and tolerability of a new facial 2-mercaptonicotinoyl glycine-containing depigmenting serum versus hydroquinone 4% over 3-month treatment of facial melasma. Dermatology and Therapy, 2025 – Melasyl
- Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial. JEADV, 2021 – Thiamidol
- MDedge Dermatology: Cysteamine and melasma (summarising Mansouri 2015 and Farshi 2018) – cysteamine
- Azelaic acid versus hydroquinone for managing patients with melasma: systematic review and meta-analysis of randomized controlled trials. Cureus, 2023 – azelaic acid for dark spots
- Garcia A, Fulton JE. The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions. Dermatologic Surgery, 1996 – kojic acid for dark spots
- Amer M, Metwalli M. Topical liquiritin improves melasma. International Journal of Dermatology, 2000 – licorice
- Evidence table of natural depigmenting agents (mulberry, licorice, aloesin and others). Journal of Clinical and Aesthetic Dermatology – mulberry
- Kimball AB and colleagues. Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine. British Journal of Dermatology, 2010 – N-acetyl glucosamine
- Hunt MJ, Barnetson RS. A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne. Australasian Journal of Dermatology, 1992 – gluconolactone
- Cochrane review: Chemical peels for acne vulgaris, 2020 – glycolic and lactic acid
- Yee BE and colleagues. Serum zinc levels and efficacy of zinc treatment in acne vulgaris: a systematic review and meta-analysis. Dermatologic Therapy, 2020 – zinc
- The efficacy and safety of azelaic acid cream 15% in the topical treatment of mild to moderate seborrheic dermatitis of the face. Damascus University Journal for Medical Sciences, 2021 – azelaic acid for seb derm
- PGA (gamma-polyglutamic acid) and hyaluronic acid: comparative study of natural moisturizers (conference poster) – polyglutamic acid
- Green BA, Edison BL, Sigler ML. Antiaging effects of topical lactobionic acid: results of a controlled usage study. Cutis, 2008 – lactobionic acid
- Zhang Y and colleagues. Characterization and topical delivery of phenylethyl resorcinol. UCL School of Pharmacy – phenylethyl resorcinol
- Mitsuishi T and colleagues. The effects of topical application of phytonadione, retinol and vitamins C and E on infraorbital dark circles and wrinkles of the lower eyelids. Journal of Cosmetic Dermatology, 2004 – vitamin K
- dos Santos Leite C and colleagues. Dipotassium glycyrrhizininate improves skin wound healing by modulating inflammatory process. International Journal of Molecular Sciences, 2023 – dipotassium glycyrrhizate
- Systematic review on transdermal/topical cannabidiol trials. Cannabis and Cannabinoid Research, 2022 – CBD
- Maia Campos PMBG and colleagues. Synergistic effects of green tea and Ginkgo biloba extracts on the improvement of skin barrier function and elasticity. Journal of Drugs in Dermatology, 2014 – ginkgo
- Vaughn AR, Branum A, Sivamani RK. Effects of turmeric (Curcuma longa) on skin health: a systematic review of the clinical evidence. Phytotherapy Research, 2016 – turmeric
- Grimes PE and colleagues. A randomized, controlled, split-face, double-blind study comparing topical malassezin to hydroquinone 4% for melasma. Journal of Drugs in Dermatology, 2026 – malassezin
- BASF: Nephoria BC 10044 (Nephelium lappaceum leaf extract) product data – rambutan
- Paula’s Choice ingredient dictionary: Bidens pilosa extract – Bidens pilosa
- Permeation of nicotinamide mononucleotide (NMN) in an artificial membrane as a cosmetic skin permeability test model, 2025 – NAD+ and NMN
- Navarrete-Solís J and colleagues. A double-blind, randomized clinical trial of niacinamide 4% versus hydroquinone 4% in the treatment of melasma. Dermatology Research and Practice, 2011 – niacinamide for melasma
- Tanno O and colleagues. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. British Journal of Dermatology, 2000 – niacinamide and the skin barrier
- Walocko FM and colleagues. The role of nicotinamide in acne treatment. Dermatologic Therapy, 2017 – niacinamide for acne (review)
- Allergic contact dermatitis from chlorphenesin in cosmetics: two new cases (UCLouvain repository) – chlorphenesin
- Multicenter study of preservative sensitivity in patients with suspected cosmetic contact dermatitis in Korea – chlorphenesin
Anti-ageing
- Topical tretinoin for treating photoaging: a systematic review of randomized controlled trials. International Journal of Women’s Dermatology, 2022 – tretinoin and prescription retinoids
- Hughes MCB, Williams GM, Baker P, Green AC. Sunscreen and prevention of skin aging: a randomized trial. Annals of Internal Medicine, 2013 – daily sunscreen and skin ageing
- Kafi R and colleagues. Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology, 2007 – retinol
- Mukherjee S and colleagues. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging, 2006 – retinal and how retinoids compare
- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. Journal of Clinical and Aesthetic Dermatology, 2017 – vitamin C and its derivatives
- Bissett DL, Oblong JE, Berge CA. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 2005 – niacinamide
- A double-blind randomized clinical trial on the effectiveness of a daily glycolic acid 5% formulation in the treatment of photoaging. Dermatologic Surgery, 1998 – glycolic acid
- US FDA: Guidance for Industry, Labeling for Cosmetics Containing Alpha Hydroxy Acids, 2005 – acids and sun sensitivity
- Stiller MJ and colleagues. Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin: a double-blind vehicle-controlled clinical trial. Archives of Dermatology, 1996 – lactic acid
- Bagatin E and colleagues. Comparable efficacy of adapalene 0.3% gel and tretinoin 0.05% cream as treatment for cutaneous photoaging. European Journal of Dermatology, 2018 – adapalene
- Dhaliwal S and colleagues. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology, 2019 – bakuchiol
- Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics, 2017 – peptides
- Pavicic T and colleagues. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology, 2011 – hyaluronic acid
- McDaniel DH, Neudecker BA, DiNardo JC, Lewis JA, Maibach HI. Clinical efficacy assessment in photodamaged skin of 0.5% and 1.0% idebenone. Journal of Cosmetic Dermatology, 2005 – idebenone
- Draelos ZD. A Double-Blind Randomized Pilot Study Evaluating the Safety and Efficacy of Topical MEP in the Facial Appearance Improvement of Estrogen Deficient Females. Journal of Drugs in Dermatology, 2018 – methyl estradiolpropanoate (MEP)
- Schmidt JB and colleagues. Treatment of skin aging with topical estrogens. International Journal of Dermatology, 1996 – estriol and estradiol creams
- Davis A and colleagues. Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing. International Journal of Cosmetic Science, 2024 – hexylresorcinol
- Milani M, Sparavigna A. Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial. Clinical, Cosmetic and Investigational Dermatology, 2018 – melatonin on the face
- Green C, Orchard G, Cerio R, Hawk JL. A clinicopathological study of the effects of topical retinyl propionate cream in skin photoageing. Clinical and Experimental Dermatology, 1998 – retinyl propionate
- Kim H and colleagues. Improvement in skin wrinkles from the use of photostable retinyl retinoate: a randomized controlled trial. British Journal of Dermatology, 2010 – retinyl retinoate
- A prospective, double-blinded, randomized head-to-head clinical trial of topical adapinoid (oleyl adapalenate) versus retinol. Skin Health and Disease, 2024 – oleyl adapalenate
- Hydroxypinacolone 9-cis retinoate mitigates UV-induced photoaging by modulating extracellular matrix, fibroblasts, inflammation, and melanogenesis. Journal of Investigative Dermatology, 2026 – 9-cis HPR against retinol
- An Innovative Serum With Retinol, Hydroxypinacolone Retinoate, Peptides, and Silybin Improves Mild Photoaged Facial Skin in Middle-Aged Chinese Women. Journal of Cosmetic Dermatology, 2025 – HPR tested in a blend
- Chien AL and colleagues. Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial. JAMA Dermatology, 2022 – the retinol and retinyl ester blend
- Miller-Kobisher B and colleagues. Epidermal Growth Factor in Aesthetics and Regenerative Medicine: Systematic Review. Journal of Cutaneous and Aesthetic Surgery, 2021 – EGF
- Beitner H. Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin. British Journal of Dermatology, 2003 – alpha lipoic acid
- Dhaliwal S and colleagues. Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging. Journal of Cosmetic Dermatology, 2020 – acetyl zingerone
- Holzer G and colleagues. Effects and side-effects of 2% progesterone cream on the skin of peri- and postmenopausal women: results from a double-blind, vehicle-controlled, randomized study. British Journal of Dermatology, 2005 – progesterone cream
- Huang H and colleagues. Topical Menaquinone-7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study. ACS Omega, 2026 – vitamin K2
- Edison BL, Green BA, Wildnauer RH, Sigler ML. A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen. Cutis, 2004 – PHAs (gluconolactone, lactobionic acid)
- Haftek M and colleagues. Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. Experimental Dermatology, 2008 – madecassoside
- Wisuitiprot W and colleagues. Effect of green tea extract loaded chitosan microparticles on facial skin: A split-face, double-blind, randomized placebo-controlled study. Journal of Cosmetic Dermatology, 2021 – green tea for ageing
- Calzavara-Pinton P and colleagues. Topical Boswellic acids for treatment of photoaged skin. Dermatologic Therapy, 2010 – boswellia
- Fabi SG, Cohen JL, Peterson JD, Kiripolsky MG, Goldman MP. The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin. Journal of Drugs in Dermatology, 2013 – snail mucin
- Topical medium-length PDRN enhances dermal extracellular matrix repair in photodamaged skin via PI3K-Akt/TGF-beta-regulated pathways. PLOS One, 2026 – PDRN (salmon DNA)
- Pillai R, Redmond M, Roding J. Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucan. International Journal of Cosmetic Science, 2005 – oat beta-glucan
- The Effectiveness of a Topical Rosehip Oil Treatment on Facial Skin Characteristics: A Pilot Study on Wrinkles, UV Spots Reduction, Erythema Mitigation, and Age-Related Signs, 2025 – rosehip oil on the face
- A systematic review and meta-analysis of 26 randomized controlled trials of hydrolyzed collagen supplementation for skin hydration and elasticity (PMC) – collagen, and why creams are different
- NoTox Tweakments: Evidence for Topical Neurocosmetic Peptides as Needle-Free Neuromodulators for Facial Wrinkle Reduction, A Systematic Review. Journal of Cosmetic Dermatology, 2026 – Argireline (acetyl hexapeptide-8)
- Abella ML. Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique. International Journal of Cosmetic Science, 2006 – adenosine
- Robinson LR and colleagues. Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International Journal of Cosmetic Science, 2005 – Matrixyl (palmitoyl pentapeptide-4)
- Grossman R. The role of dimethylaminoethanol in cosmetic dermatology. American Journal of Clinical Dermatology, 2005 – DMAE
- Efficacy and Safety of Centella Asiatica (L.) Urb. on Wrinkles: A Systematic Review of Published Data and Network Meta-Analysis. Journal of Cosmetic Science, 2020 – centella (cica)
- Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial. Frontiers in Aging, 2025 – resveratrol
- Linus Pauling Institute, Oregon State University: Vitamin E and Skin Health – vitamin E
- The Role of Coenzyme Q10 in Skin Aging. Journal of Clinical and Aesthetic Dermatology, 2025 – CoQ10 (ubiquinone)
- Collagen concentration on the facial skin of postmenopausal women after topical treatment with estradiol and genistein: a randomized double-blind controlled trial. Gynecological Endocrinology, 2017 – genistein (soy isoflavone)
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences, 2018 – copper peptide on the face
- Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing, 2021 – astaxanthin
- Evaluation of Caffeine Gels on Physicochemical Characteristics and In Vivo Efficacy in Reducing Puffy Eyes, 2010 – caffeine in eye products
- How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients? Journal of Clinical and Aesthetic Dermatology – kinetin for sun-damaged skin
- Korean Red Ginseng skin whitening and anti-ageing study, including a human cream test. Journal of Ginseng Research, 2020 – ginseng
- In vivo assessment of Ectoin: a randomized, vehicle-controlled clinical trial. Skin Pharmacology and Physiology, 2007 – ectoin
- McDaniel DH. Clinical Safety and Efficacy in Photoaged Skin With CoffeeBerry Extract, a Natural Antioxidant. Cutis, 2009 – coffeeberry
- Objective assessment of skin elasticity after topical mandelic acid. Facial Plastic Surgery, 2018 – mandelic acid
- Lin FH and colleagues. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 2005 – ferulic acid
- Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula, 2021 – Galactomyces (Pitera)
- Supplier data sheet: Pro-Xylane (hydroxypropyl tetrahydropyrantriol) – Pro-Xylane and its in-house test figures
- Savić S, Cekić N et al. All-natural anti-wrinkle emulsion serum with Acmella oleracea extract. International Journal of Cosmetic Science, 2021 – Acmella oleracea
- Park HS, Shin S. Clinical Efficacy and Safety Evaluation of a Centella asiatica (CICA)-Derived Extracellular Vesicle Formulation for Anti-Aging Skincare. Cosmetics, 2025 – exosomes
- Watanabe F and colleagues. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 2014 – glutathione
- Han SM and colleagues. The beneficial effects of honeybee-venom serum on facial wrinkles in humans. Clinical Interventions in Aging, 2015 – bee venom
- Schmid D. Stimuli for skin stem cells for real skin rejuvenation. Mibelle Biochemistry, 2009 – apple stem cells (maker study)
Sensitive skin and eczema
- Botvid S and colleagues. Contact sensitization to fragrance mix I and fragrance mix II among European dermatitis patients: a systematic review. Contact Dermatitis, 2024 – fragrance allergy rates
- Owen JL, Vakharia PP, Silverberg JI. The role and diagnosis of allergic contact dermatitis in patients with atopic dermatitis. American Journal of Clinical Dermatology, 2018 – fragrance, lanolin, formaldehyde and daisy family allergens in eczema
- de Groot AC and colleagues. Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 1. Contact Dermatitis, 2010 – formaldehyde releasers
- McGowan MA, Scheman A, Jacob SE. Propylene glycol in contact dermatitis: a systematic review. Dermatitis, 2018 – propylene glycol
- Bandier J and colleagues. Skin reaction and regeneration after single sodium lauryl sulfate exposure stratified by filaggrin genotype and atopic dermatitis phenotype. British Journal of Dermatology, 2015 – SLS
- Schnuch A and colleagues. Is cocamidopropyl betaine a contact allergen? Analysis of network data and short review of the literature. Contact Dermatitis, 2011 – why cocamidopropyl betaine is not flagged
- Danby SG and colleagues. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care. Pediatric Dermatology, 2013 – olive oil and sunflower seed oil
- Ma L and colleagues. Prolonging time to flare in pediatric atopic dermatitis: a randomized, investigator-blinded, controlled, multicenter clinical study of a ceramide-containing moisturizer. Advances in Therapy, 2017 – ceramides
- Lisante TA, Nuñez C, Zhang P. Efficacy and safety of an over-the-counter 1% colloidal oatmeal cream in the management of mild to moderate atopic dermatitis in children. Journal of Dermatological Treatment, 2017 – colloidal oatmeal
- Åkerström U and colleagues. Comparison of moisturizing creams for the prevention of atopic dermatitis relapse. Acta Dermato-Venereologica, 2015 – urea
- Fragrance allergen labelling and the methylisothiazolinone ban use the two EU regulations listed under Rosacea
Other ingredient checkers I compared against
These are other checkers and ingredient lists I compared my results with. They are not research, so none of the flags in this checker use them as their source.
- SkinSort: Fungal Acne (Malassezia) Ingredient Checker – their fungal acne trigger list
- SkinSort: Seborrheic Dermatitis Ingredient Checker – their seb derm checker, which uses the same trigger list as fungal acne
- SkinSort: Pore Clogging and Comedogenic Ingredient Checker – their list of ingredients rated 2 or higher for pore clogging
- SkinSort: Understanding fungal acne triggers – their guide to trigger types, including squalene
- SkinSort: PEG-70 Lanolin – their notes on lanolin ingredients
- SkinSort: ingredient notes on beeswax, candelilla wax and carnauba wax – their notes on natural waxes
- Folliculitis Scout: How We Decide – their method for judging which ingredients feed Malassezia
- Folliculitis Scout: Cetearyl Alcohol – their ingredient page for cetearyl alcohol
- Sezia (sezia.co): Sources – the research list their checker is built on
- Sezia (sezia.com): C12-C15 Alkyl Benzoate – their rating for C12-15 alkyl benzoate
- Simple Skincare Science: Fungal Acne Safe Products – their fungal acne product and ingredient guide
- With and Within: Malassezia folliculitis trigger ingredient list – their trigger ingredient list
- Fungalscan: fungal acne ingredient index – their ratings for over 700 ingredients